Leptomeningeal Carcinomatosis in a Young Patient With Colorectal Cancer: A Case Report

Leptomeningeal carcinomatosis (LMC) is a rare and fatal complication associated with various solid tumors and hematological malignancies. It presents significant diagnostic challenges due to its nonspecific symptoms and complex clinical course. This case report details the presentation, diagnosis, and implications of LMC in a 33-year-old male with a history of colorectal cancer (CRC) and hemicolectomy. The patient presented with nonspecific symptoms of headache and dizziness. Cerebrospinal fluid cytology revealed the presence of malignant cells, leading to the diagnosis of LMC secondary to CRC. The elusive and multifaceted nature of this condition highlights the necessity for increased clinical awareness and extensive research to improve the understanding and management of LMC.

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Publication Details

Journal
Cureus
Published
2024-09-03
DOI
https://doi.org/10.7759/cureus.68519
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Leptomeningeal Carcinomatosis in a Young Patient With Colorectal Cancer: A Case Report

Sayed K. Ali, Soraiya Manji, Sheila Waa, Rajiv Patel et al.
Cureus
Brain Metastases and Treatment
article

Leptomeningeal Carcinomatosis in a Young Patient With Colorectal Cancer: A Case Report

Sayed K. Ali, Soraiya Manji, Sheila Waa, Rajiv Patel, Karishma Sharma, Zamanali Khakhar
article en

Abstract

Leptomeningeal carcinomatosis (LMC) is a rare and fatal complication associated with various solid tumors and hematological malignancies. It presents significant diagnostic challenges due to its nonspecific symptoms and complex clinical course. This case report details the presentation, diagnosis, and implications of LMC in a 33-year-old male with a history of colorectal cancer (CRC) and hemicolectomy. The patient presented with nonspecific symptoms of headache and dizziness. Cerebrospinal fluid cytology revealed the presence of malignant cells, leading to the diagnosis of LMC secondary to CRC. The elusive and multifaceted nature of this condition highlights the necessity for increased clinical awareness and extensive research to improve the understanding and management of LMC.

CureusVol. 16(9)
University of Nairobi (KE), Aga Khan University Hospital Nairobi (KE), Aga Khan University Nairobi (KE), Primary HealthCare (MT)
Good health and well-being
Openalex Percentile: Top 74%
Brain Metastases and Treatment
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Leptomeningeal Carcinomatosis in a Young Patient With Colorectal Cancer: A Case Report — Sayed K. Ali, Soraiya Manji, et al. · Cureus (2024) | TGRS Research Map | TGRS