Transcriptomic Landscape of Colorectal Mucinous Adenocarcinoma has Similarity with Intestinal Goblet Cell Differentiation
This study suggests that clinical treatments for colorectal MC should be differentiated from AD. Further exploration of enterocyte (goblet cell) differentiation with tumor genesis and the distinct immune progression of MC may help to identify key therapeutic targets for colorectal MC. Further research on the application of immunotherapy to colorectal MC is needed.
Authors
- Lie Yang (ORCID: https://orcid.org/0000-0003-1178-7147)
- Zong‐Guang Zhou (ORCID: https://orcid.org/0000-0002-4252-0341)
- Zhaoying Lv
- Yuan Li (ORCID: https://orcid.org/0000-0001-7110-4622)
- Ruijuan Zu
- Bin Zhou (ORCID: https://orcid.org/0000-0001-5278-5522)
- Jianbo Liu (ORCID: https://orcid.org/0000-0002-0507-1508)
- Siyuan Qiu
- Xiaorui Fu
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Current Genomics
- Published
- 2024-09-03
- DOI
- https://doi.org/10.2174/0113892029312303240821080358
- Citations
- 6
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- West China Hospital, Sichuan University