A Novel Next-Generation Sequencing Assay for the Identification of <i>BCR</i>::<i>ABL1</i> Transcript Type and Accurate and Sensitive Detection of TKI-Resistant Mutations
The Dup-Seq BCR::ABL1 assay not only allows for the identification of BCR::ABL1 typical and atypical transcript types and accurate and sensitive detection of TKI-resistant mutations but also simplifies molecular testing work flow for the clinical management of CML patients.
Authors
- Zhenyu Yan (ORCID: https://orcid.org/0000-0003-4972-0095)
- Chad Galderisi
- Weihua Liu (ORCID: https://orcid.org/0009-0009-5593-9545)
- Jin Li (ORCID: https://orcid.org/0000-0001-8526-4395)
- Lin Shi
- Wei Li (ORCID: https://orcid.org/0000-0002-8572-9225)
- Cynthia Spittle
Institutions
- Imperial Consultants (GB)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1093/jalm/jfae096
- Citations
- 5
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.27