Analysis of Unfolded Protein Response Activation in Colon Adenocarcinoma Epithelial Cells: A Proteomic Study
CRC cell lines at different tumour grades expressed different functional programmes at the proteomic level and were characterised by different responses to the UPR induction. This study suggests that baseline cancer cell stress status could have an impact on the efficiency of cancer therapies.
Authors
- David Launay (ORCID: https://orcid.org/0000-0003-1840-1817)
- Vincent Sobanski (ORCID: https://orcid.org/0000-0003-3083-2441)
- Solange Vivier (ORCID: https://orcid.org/0000-0002-7640-9465)
- Fabrice Bray (ORCID: https://orcid.org/0000-0002-4723-8206)
- Lucile Guilbert (ORCID: https://orcid.org/0000-0002-8157-8052)
- Stéphanie Flament (ORCID: https://orcid.org/0000-0002-0135-675X)
- Florence Renaud (ORCID: https://orcid.org/0000-0003-3614-1713)
- Christian Rolando (ORCID: https://orcid.org/0000-0002-3266-8860)
- Sylvain Dubucquoi (ORCID: https://orcid.org/0000-0002-8962-3719)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut Universitaire de France (FR)
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Sorbonne Université (FR)
- Hôpital Nord (FR)
- Miniaturisation pour la Synthèse, l'Analyse et la Protéomique (FR)
- Lille Inflammation Research International Center (FR)
- Centre de Recherche Saint-Antoine (FR)
- Institut de Biologie de Lille (FR)
- Institute for Translational Research in Inflammation (FR)
Publication Details
- Journal
- PROTEOMICS - CLINICAL APPLICATIONS
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1002/prca.202400008
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Infrastructures en Biologie Santé et Agronomie
- Université de Lille
- Agence Nationale de la Recherche
- Centre National de la Recherche Scientifique
- Région Hauts-de-France
- European Regional Development Fund