Effects of arketamine on depression-like behaviors and demyelination in mice exposed to chronic restrain stress: A role of transforming growth factor-β1
These data suggest that CRS-induced demyelination in the corpus callosum may contribute to depression-like behaviors, and that arketamine can mitigate these changes through a TGF-β1-dependent mechanism.
Authors
- Rumi Murayama
- Youge Qu (ORCID: https://orcid.org/0000-0002-3579-8628)
- Kenji Hashimoto (ORCID: https://orcid.org/0000-0002-8892-0439)
- Xiayun Wan (ORCID: https://orcid.org/0000-0002-5173-2071)
- Dan Xu (ORCID: https://orcid.org/0000-0003-0548-3833)
- Guilin Liu (ORCID: https://orcid.org/0000-0003-4286-5187)
- Mingming Zhao
Institutions
- Qingdao University (CN)
- Union Hospital (HK)
- Chiba University (JP)
- Affiliated Hospital of Qingdao University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Center for Forensic Mental Health, Chiba University (JP)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1016/j.jad.2024.08.222
- Citations
- 19
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.99
Funders
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency