A novel biomarker GATM suppresses proliferation and malignancy of cholangiocarcinoma cells by modulating the JNK/c-Jun signalling pathways
GATM acts as a tumour suppressor in CCA by regulating the phosphorylation of the JNK/c-Jun pathway. IDH1 interacted with GATM to regulate CCA progression.
Authors
- Wei Gan
- Jianping Xiong (ORCID: https://orcid.org/0000-0003-0398-6090)
- Junhe Li
- Yi Yu
Institutions
- Nanchang University (CN)
- Sun Yat-sen University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37344
- Citations
- 2
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.57