Investigation of hepatic inflammation via viscoelasticity at low and high mechanical frequencies - A magnetic resonance elastography study
Our results suggest that c-dispersion of the liver is sensitive to inflammation when measured in-vivo in the low dynamic range (30-60Hz), while at higher frequencies (0.8-2.8 kHz) viscoelastic parameters are dominated by fibrosis.
Authors
- Christian Bayerl (ORCID: https://orcid.org/0000-0001-7107-3934)
- Kai S. Lehmann (ORCID: https://orcid.org/0000-0003-0479-3821)
- Bernd Hamm (ORCID: https://orcid.org/0000-0002-9141-027X)
- Vanessa Proß (ORCID: https://orcid.org/0000-0003-1489-9494)
- Patrick Asbach (ORCID: https://orcid.org/0000-0002-6885-3283)
- Anja A. Kühl (ORCID: https://orcid.org/0000-0003-2293-5387)
- Rolf Reiter (ORCID: https://orcid.org/0000-0002-9741-6736)
- Marcus R. Makowski (ORCID: https://orcid.org/0000-0001-8778-647X)
- Yasmine Safraou (ORCID: https://orcid.org/0009-0009-7347-1552)
- Ingolf Sack (ORCID: https://orcid.org/0000-0003-2460-1444)
- Jürgen Braun (ORCID: https://orcid.org/0000-0001-5183-7546)
- Mehrgan Shahryari (ORCID: https://orcid.org/0000-0002-3981-1711)
Institutions
- TUM Klinikum (DE)
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Technical University of Munich (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1016/j.jmbbm.2024.106711
- Citations
- 6
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- Deutsche Forschungsgemeinschaft