HIV-1 residual risk and pre-treatment drug resistance among blood donors: A sentinel surveillance from Gabon
This sentinel surveillance indicates a high residual risk of HIV-1 transfusion in Gabon, thereby underscoring the need for optimal screening strategy for blood safety. Moreover, HIV-1 transmission goes with high-risk of PDR, suggesting suboptimal efficacy of ART. Nonetheless, the genetic diversity has limited (if any effect) on the residual risk of infection and PDR in blood donors.
Authors
- Hortense Kamga Gonsu
- Grâce Beloumou (ORCID: https://orcid.org/0000-0002-6870-7366)
- Nadine Fainguem (ORCID: https://orcid.org/0000-0002-8497-7948)
- Thérèse Nkoa
- Rachel Kamgaing (ORCID: https://orcid.org/0000-0001-6354-1400)
- Alex Durand Nka (ORCID: https://orcid.org/0000-0002-9358-8661)
- Olga Boussougou
- Ezéchiel Ngoufack Jagni Semengue (ORCID: https://orcid.org/0000-0001-8768-2371)
- Denis Maulot-Bangola (ORCID: https://orcid.org/0000-0002-6822-4356)
- Vicky Jocélyne Ama Moor (ORCID: https://orcid.org/0000-0003-1984-103X)
- Alexis Ndjolo (ORCID: https://orcid.org/0000-0002-4951-9271)
- Christian Mangala (ORCID: https://orcid.org/0000-0002-8367-5497)
- Franck Vigan Codjo
- Collins Ambe Chenwi (ORCID: https://orcid.org/0000-0002-6749-1436)
- Vittorio Colizzi (ORCID: https://orcid.org/0000-0003-0007-8580)
- Joseph Fokam
- Michel Carlos Tommo Tchouaket (ORCID: https://orcid.org/0000-0002-7186-8515)
- Carlo Federico Perno (ORCID: https://orcid.org/0000-0002-0825-5388)
- Olivier Rebienot Pellegrin
- Véronique Penlap
- Désiré Takou
- Samuel Martin Sosso
Institutions
- University of Rome Tor Vergata (IT)
- Université de Yaoundé I (CM)
- University of Buea (CM)
- Libreville Hospital (GA)
- Centre International De Reference Chantal Biya (CM)
- Bambino Gesù Children's Hospital (IT)
- Ministry of Public Health (CM)
- Catholic University of Central Africa (CM)
- University Teaching Hospital of Yaounde (CM)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1371/journal.pone.0305935
- Citations
- 4
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.56