Safety and Efficacy Comparison of Tenecteplase and Alteplase for Clinically Suspected Large Vessel Occlusion Strokes without Thrombectomy

In this pragmatic study of clinically suspected anterior circulation LVO patients without thrombectomy, outcome solely reflects the effects of tenecteplase. Tenecteplase showed comparable safety and efficacy to alteplase, but the result should be interpreted with caution in view of its small sample size and non-randomised study design.

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Publication Details

Journal
Cerebrovascular Diseases Extra
Published
2024-09-03
DOI
https://doi.org/10.1159/000540750
Citations
1
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.39
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article

Safety and Efficacy Comparison of Tenecteplase and Alteplase for Clinically Suspected Large Vessel Occlusion Strokes without Thrombectomy

N CHAN, Moamina Ismail, Jessica Tsz Ching Li, Man Sin Wong et al.
1 citations
Cerebrovascular Diseases Extra
Acute Ischemic Stroke Management
0.39
article

Safety and Efficacy Comparison of Tenecteplase and Alteplase for Clinically Suspected Large Vessel Occlusion Strokes without Thrombectomy

N CHAN, Moamina Ismail, Jessica Tsz Ching Li, Man Sin Wong, Chong Ching Chan, Andrew L. Chan, Y F Cheung, Shun Tim Chan, Hiu Fan Or, Ching Shing Fong, Wai Ting Lo, Chris Siu Kwan Chau, Chi Him Simon Chan, Chung Yuen Chan, Germaine Hui-Fai Chan, Wing Chi Fong, Wai Yan Vivian Kwok
article en
1 citations

Abstract

In this pragmatic study of clinically suspected anterior circulation LVO patients without thrombectomy, outcome solely reflects the effects of tenecteplase. Tenecteplase showed comparable safety and efficacy to alteplase, but the result should be interpreted with caution in view of its small sample size and non-randomised study design.

Cerebrovascular Diseases ExtraVol. 14(1)
Queen Elizabeth Hospital (CN)
Good health and well-being
Openalex Percentile: Top 35%
Acute Ischemic Stroke Management
0.39
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Safety and Efficacy Comparison of Tenecteplase and Alteplase for Clinically Suspected Large Vessel Occlusion Strokes without Thrombectomy — N CHAN, Moamina Ismail, et al. · Cerebrovascular Diseases Extra (2024) | TGRS Research Map | TGRS