Dihydromyricetin suppresses endothelial NLRP3 inflammasome activation and attenuates atherogenesis by promoting mitophagy
This study suggested that dihydromyricetin may function as a modulator to promote mitophagy, which in turn mitigates NF-κB activity and subsequent NLRP3 inflammasome activation, thereby conferring protection against atherosclerosis.
Authors
- Tongjian Cai (ORCID: https://orcid.org/0000-0003-3188-6265)
- Qin Hu (ORCID: https://orcid.org/0000-0002-2270-8822)
- Cheng-Ying Li (ORCID: https://orcid.org/0000-0002-5958-0164)
- Yifan Shan (ORCID: https://orcid.org/0009-0007-5585-0298)
- Ran Li (ORCID: https://orcid.org/0000-0002-3365-6773)
- Yafei Li (ORCID: https://orcid.org/0000-0001-8812-0733)
- Ting Zhang (ORCID: https://orcid.org/0000-0003-0099-9670)
- Long Yi (ORCID: https://orcid.org/0000-0002-3831-6014)
- Xiangyu Ma (ORCID: https://orcid.org/0000-0001-7967-3950)
- Hui Shen (ORCID: https://orcid.org/0000-0002-8178-4614)
Institutions
- Army Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1186/s12944-024-02263-1
- Citations
- 13
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China
- Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission