Green synthesis of sacrificial UV-sensitive core and biobased shell for obtaining optically hollow nanoparticles

Hollow nanoparticles have been extensively studied in recent years. Obtaining such structures with biobased materials, following greener synthetic routes, is still challenging, especially if accurate particle dimensions are required. This work reports the use of an innovative hybrid silica core (Si@azo) containing UV-sensitive molecule, wrapped in biobased multilayer shell composed of polysaccharides. It is a promising strategy for obtaining optically hollow nanoparticles. Indeed, Si@azo cores have the ability to be partially degraded when irradiated with UV light. Combined with a well-controlled and monodisperse diameter, they provide a good basis for layer-by-layer assembly, leading to a multilayer shell with controlled composition and thickness. Finally, UV irradiation of such a core-shell structure is harmless to the polysaccharide shell, but does impact the hybrid silica core, as revealed by turbidity measurements, among other. Each step, i.e. core synthesis, shell addition, and core-shell irradiation, has been carefully characterized at the macro (Fourier-transform infrared spectroscopy - FTIR, Dynamic Light Scattering - DLS, Zeta-potential measurement, Surface Plasmon Resonance - SPR, turbidity) and microscale (Transmission and Scanning Electron Microscopies). Emphasis is put on how turbidity measurements can be related to the core refractive index (n_core), giving information on the state of core degradation and whether the core-shell particle is optically hollow.