From Diagnosis to Resolution: A Case Study of Myxopapillary Ependymoma Survival

Myxopapillary ependymoma (MPE) is a rare, slow-growing tumor that commonly arises in the lumbosacral region of the spinal cord, within the filum terminale and cauda equina. The frequent presentation of MPE is back, sacral, or leg pain. The tumor's size, site, and extension usually influence these symptoms. MPE is usually evaluated using magnetic resonance imaging (MRI) because of its superior soft tissue contrast. The best treatment modality is total surgical resection, which improves the long-term survival rate, with follow-up imaging recommended to ensure total resolution. Here, we present the case of a 29-year-old male who presented with symptoms suggestive of severe neurological impairment. An MRI scan revealed an intradural lesion arising from the cauda equina with peripheral and intrathecal haemorrhage, consistent with MPE. He was managed with laminectomy and microsurgical resection of the tumor, which achieved total resection. Postoperative follow-up found gradual improvement in his symptoms, and routine surveillance imaging confirmed the complete resolution of the tumor.

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Journal
Cureus
Published
2024-09-02
DOI
https://doi.org/10.7759/cureus.68490
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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From Diagnosis to Resolution: A Case Study of Myxopapillary Ependymoma Survival

Mohamed Hassan, Mohammed Al-Banna, Mahmoud Abughazal, Moustafa Abouelkheir et al.
Cureus
Glioma Diagnosis and Treatment
article

From Diagnosis to Resolution: A Case Study of Myxopapillary Ependymoma Survival

Mohamed Hassan, Mohammed Al-Banna, Mahmoud Abughazal, Moustafa Abouelkheir, Mustafa Aljanabi
article en

Abstract

Myxopapillary ependymoma (MPE) is a rare, slow-growing tumor that commonly arises in the lumbosacral region of the spinal cord, within the filum terminale and cauda equina. The frequent presentation of MPE is back, sacral, or leg pain. The tumor's size, site, and extension usually influence these symptoms. MPE is usually evaluated using magnetic resonance imaging (MRI) because of its superior soft tissue contrast. The best treatment modality is total surgical resection, which improves the long-term survival rate, with follow-up imaging recommended to ensure total resolution. Here, we present the case of a 29-year-old male who presented with symptoms suggestive of severe neurological impairment. An MRI scan revealed an intradural lesion arising from the cauda equina with peripheral and intrathecal haemorrhage, consistent with MPE. He was managed with laminectomy and microsurgical resection of the tumor, which achieved total resection. Postoperative follow-up found gradual improvement in his symptoms, and routine surveillance imaging confirmed the complete resolution of the tumor.

CureusVol. 16(9)
United Lincolnshire Hospitals NHS Trust (GB)
Zero hunger
Openalex Percentile: Top 76%
Glioma Diagnosis and Treatment
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From Diagnosis to Resolution: A Case Study of Myxopapillary Ependymoma Survival — Mohamed Hassan, Mohammed Al-Banna, et al. · Cureus (2024) | TGRS Research Map | TGRS