Remote ischemic preconditioning prevents high‐altitude cerebral edema by enhancing glucose metabolic reprogramming
Our study elucidates the metabolic basis of HACE pathogenesis. This study provides a new strategy for preventing HACE that RIPC reduces brain edema through reprogramming metabolism, highlighting the potential of targeting metabolic reprogramming for neuroprotective interventions in neurological diseases caused by ischemia or hypoxia.
Authors
- Xunming Ji (ORCID: https://orcid.org/0000-0003-0293-2744)
- Rongrong Han (ORCID: https://orcid.org/0009-0000-5176-8480)
- Bing Zhou (ORCID: https://orcid.org/0000-0002-7718-2311)
- Xiaoyan Yang
Institutions
- Capital Medical University (CN)
- Beihang University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/cns.70026
- Citations
- 12
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 6.60
Funders
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Beijing Municipal Natural Science Foundation