Ameliorative effects of Monascus-fermented hawthorn extract on a high-fat diet-induced rat model of non-alcoholic fatty liver disease
Our findings suggested that fermented hawthorn extract can markedly reduce body weight, ameliorate HFD-induced NAFLD in rats, and exhibits significant antioxidant effects. Its underlying mechanism may depend on the inhibition of CYP2E1, SREBP-1c, and FAS expression.
Authors
- Kaixin Wang (ORCID: https://orcid.org/0000-0002-6650-2850)
- Ruyun Zhou
- Mei‐Juan Xie
- Zhiqiang Gao
- Libo Chen (ORCID: https://orcid.org/0000-0002-7755-6408)
- Jiang Li (ORCID: https://orcid.org/0000-0001-7132-5302)
- Juan Zhang
Institutions
- Union Hospital (HK)
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- ShenZhen People’s Hospital (CN)
- Shenzhen University Health Science Center (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37354
- Citations
- 4
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.87