cRGD-platelet@MnO/MSN@PPARα/LXRα Nanoparticles Improve Atherosclerosis in Rats by Inhibiting Inflammation and Reducing Blood Lipid
The newly developed cRGD-platelet-NPs with high safety are a promising approach to AS treatment, which can regulate ABCA1, reduce the formation of AS plaques, and enhance cholesterol efflux. The mechanism may involve the suppression of the NF-κB signaling pathway.
Authors
- Zheng Lv
- Yupeng Zhang (ORCID: https://orcid.org/0000-0002-7116-2192)
- Mengke Lu
- Ziyi Wang (ORCID: https://orcid.org/0000-0002-4681-6588)
- Wei Zhang (ORCID: https://orcid.org/0000-0003-2255-5405)
- Guoliang Wen
- Xiaoyue Nong
Institutions
- Guilin Medical University (CN)
- Liuzhou General Hospital (CN)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2024-09-03
- DOI
- https://doi.org/10.2174/0113892010314993240819065655
- Citations
- 3
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.86