QSAR Studies on a Class of Benzofuranene Cyanide Derivatives as Potential Inhibitors Targeting Staphylococcus aureus Sortase A

In this study, two quantitative structure-activity relationship models were successfully established to predict the inhibitory activity of a series of compounds targeting Staphylococcus aureus Sortase A, providing insights for further development of novel anti-Staphylococcus aureus drugs.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2024-09-03
DOI
https://doi.org/10.2174/0109298673300334240821041349
Primary Topic
Biochemical and Structural Characterization
Type
article
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article

QSAR Studies on a Class of Benzofuranene Cyanide Derivatives as Potential Inhibitors Targeting Staphylococcus aureus Sortase A

Jinqiu Zhang, Shaodong Fu, Yawei Qiu, Jinfeng Miao et al.
2 links
Current Medicinal Chemistry
Biochemical and Structural Characterization
article

QSAR Studies on a Class of Benzofuranene Cyanide Derivatives as Potential Inhibitors Targeting Staphylococcus aureus Sortase A

Jinqiu Zhang, Shaodong Fu, Yawei Qiu, Jinfeng Miao, Bo Yang
article en

Abstract

In this study, two quantitative structure-activity relationship models were successfully established to predict the inhibitory activity of a series of compounds targeting Staphylococcus aureus Sortase A, providing insights for further development of novel anti-Staphylococcus aureus drugs.

Current Medicinal ChemistryVol. 32(34)
Nanjing Agricultural University (CN), Jiangsu Academy of Agricultural Sciences (CN)
Good health and well-being
Openalex Percentile: Top 87%
Biochemical and Structural Characterization
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