Oxidation of NOBINs Toward α-Spiropyrrolidones
While the oxidation of phenols and BINOLs is well documented to lead to a broad range of useful organic scaffolds, that of NOBINs is far less explored. We investigate herein their oxidation with a number of standard chemical oxidants, leading upon skeletal rearrangement to the corresponding α-spiropyrrolidones, which represent a rare and highly valuable heterocyclic core.
Authors
- Iris M. Oppel (ORCID: https://orcid.org/0000-0002-8702-9003)
- Yun Yang (ORCID: https://orcid.org/0000-0002-8661-7444)
- Ben Ebel (ORCID: https://orcid.org/0009-0003-7049-6013)
- Frédéric W. Patureau (ORCID: https://orcid.org/0000-0002-4693-7240)
Institutions
- RWTH Aachen University (DE)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1021/acs.orglett.4c02499
- Citations
- 1
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- China Scholarship Council