Poor outcome despite modern treatments: A retrospective study of 99 patients with primary and secondary plasma cell leukemia
This study is one of the largest PCL cohorts reported. We are also the first to investigate characteristics of MM before its transformation into sPCL and demonstrate that high-risk biologic features already present at the time of MM diagnosis. Moreover, our data highlights the lack of improvement in PCL survival in recent years and the urgent need for better treatment options.
Authors
- Jean Roy (ORCID: https://orcid.org/0000-0002-7716-6864)
- Richard Leblanc (ORCID: https://orcid.org/0000-0002-9982-0919)
- Jean‐Samuel Boudreault (ORCID: https://orcid.org/0000-0003-4737-9153)
- Marc Lalancette (ORCID: https://orcid.org/0000-0003-1161-3972)
- Rayan Kaedbey (ORCID: https://orcid.org/0000-0002-8556-4926)
- Julie Anne Côté (ORCID: https://orcid.org/0000-0003-1383-2984)
- Émilie Lemieux‐Blanchard
- Camille Tessier (ORCID: https://orcid.org/0009-0009-8168-3782)
- Sabrina Trudel
- Michel Pavic (ORCID: https://orcid.org/0000-0002-7057-7492)
Institutions
- Université de Sherbrooke (CA)
- Jewish General Hospital (CA)
- Centre Hospitalier Universitaire de Sherbrooke (CA)
- Hôpital Maisonneuve-Rosemont (CA)
- Centre hospitalier universitaire de Québec (CA)
- Hôpital Charles-Le Moyne (CA)
- Hôtel-Dieu de Québec (CA)
- Hôpital de l'Enfant-Jésus (CA)
- Hôpital du Sacré-Cœur de Montréal (CA)
- Centre Hospitalier de l’Université de Montréal (CA)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/cam4.70192
- Citations
- 4
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Université de Sherbrooke