Motor-free telerobotic endomicroscopy for steerable and programmable imaging in complex curved and localized areas

Intraluminal epithelial abnormalities, potential precursors to significant conditions like cancer, necessitate early detection for improved prognosis. We present a motor-free telerobotic optical coherence tomography (OCT) endoscope that offers high-resolution intraluminal imaging and overcomes the limitations of traditional systems in navigating curved lumens. This system incorporates a compact magnetic rotor with a rotatable diametrically magnetized cylinder permanent magnet (RDPM) and a reflector, effectively mitigating thermal and electrical risks by utilizing an external magnetic field to maintain temperature increases below 0.5 °C and generated voltage under 0.02 mV. Additionally, a learning-based method corrects imaging distortions resulting from nonuniform rotational speeds. Demonstrating superior maneuverability, the device achieves steerable angles up to 110° and operates effectively in vivo, providing distortion-free 3D programmable imaging in mouse colons. This advancement represents a significant step towards guidewire-independent endomicroscopy, enhancing both safety and potential patient outcomes.

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Publication Details

Journal
Nature Communications
Published
2024-09-03
DOI
https://doi.org/10.1038/s41467-024-51633-x
Citations
31
Primary Topic
Soft Robotics and Applications
Type
article
Field-Weighted Citation Impact
5.72

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OCT
article

Motor-free telerobotic endomicroscopy for steerable and programmable imaging in complex curved and localized areas

Beilei Cui, Hongliang Ren, Tinghua Zhang, Wu Yuan et al.
31 citations
Nature Communications
Soft Robotics and Applications
5.72
article

Motor-free telerobotic endomicroscopy for steerable and programmable imaging in complex curved and localized areas

Beilei Cui, Hongliang Ren, Tinghua Zhang, Wu Yuan, Sishen Yuan, Baijia Liang, Chao Xu
article en
31 citations

Abstract

Intraluminal epithelial abnormalities, potential precursors to significant conditions like cancer, necessitate early detection for improved prognosis. We present a motor-free telerobotic optical coherence tomography (OCT) endoscope that offers high-resolution intraluminal imaging and overcomes the limitations of traditional systems in navigating curved lumens. This system incorporates a compact magnetic rotor with a rotatable diametrically magnetized cylinder permanent magnet (RDPM) and a reflector, effectively mitigating thermal and electrical risks by utilizing an external magnetic field to maintain temperature increases below 0.5 °C and generated voltage under 0.02 mV. Additionally, a learning-based method corrects imaging distortions resulting from nonuniform rotational speeds. Demonstrating superior maneuverability, the device achieves steerable angles up to 110° and operates effectively in vivo, providing distortion-free 3D programmable imaging in mouse colons. This advancement represents a significant step towards guidewire-independent endomicroscopy, enhancing both safety and potential patient outcomes.

Nature CommunicationsVol. 15(1)
Chinese University of Hong Kong (HK)
National Natural Science Foundation of China, Chinese University of Hong Kong, Innovation and Technology Fund
Affordable and clean energy
Openalex Percentile: Top 3%
Soft Robotics and Applications
5.72
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