Tumor microenvironment-responsive manganese-based nano-modulator activate the cGAS-STING pathway to enhance innate immune system response
This HA-modified manganese-based hybrid nano-regulator can enhance antitumor therapy by boosting innate immune activity and may provide new directions for immunotherapy and clinical translation in cancer.
Authors
- Xiayi Liang (ORCID: https://orcid.org/0009-0008-6876-6543)
- Xiaofeng Dong (ORCID: https://orcid.org/0000-0003-2099-2652)
- Siyang Yao
- Yuanquan Zhao
- Duo Wang (ORCID: https://orcid.org/0000-0002-5390-8632)
- Xiaobo Wang (ORCID: https://orcid.org/0000-0001-6982-8058)
- Jian‐Rong Yang (ORCID: https://orcid.org/0000-0002-7807-9455)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-7769-7377)
- Yong‐Yu Yang
- Wei Huang (ORCID: https://orcid.org/0009-0008-8404-3409)
Institutions
- Zhongda Hospital Southeast University (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1186/s12951-024-02809-6
- Citations
- 28
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 5.16
Funders
- National Natural Science Foundation of China
- Science and Technology Major Project of Guangxi