Changes in Circulating CD44+CD62L− Treg Subsets and CD44−CD62L+ Treg Subsets Reflect the Clinical Status of Patients with Allergic Rhinitis
A greater proportion of CD44+CD62L- Tregs correlated with better reversal of the Th1/Th2 imbalance and milder clinical symptoms in AR patients. The presence of more CD44-CD62L+ Tregs correlated with a weaker immunosuppressive effect on Th2 cells and more severe clinical symptoms in AR patients. These findings provide new perspectives for the treatment and disease monitoring of AR.
Authors
- Yue-Long Qiao
- Wo-Er Jiao
- Zezhang Tao
- Shan Xu
- Shiming Chen (ORCID: https://orcid.org/0000-0002-1216-004X)
- Jiayu Liu (ORCID: https://orcid.org/0000-0001-6976-4568)
Institutions
- University of Zurich (CH)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1159/000540536
- Citations
- 1
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.38