Zoster Sine Herpete Affecting Multiple Lower Cranial Nerves Presenting Severe Dysphagia in a Patient with Parkinson's Disease

We report the case of a 74-year-old woman with Parkinson's disease (PD) who developed acute dysphagia, dysarthria, and hoarseness. A neurological examination and nasopharyngeal fiberscopy revealed paralysis of the left glossopharyngeal, vagus, and hypoglossal nerves. No skin rash was observed. Cerebrospinal fluid testing showed lymphocytic pleocytosis, and an elevated varicella-zoster virus (VZV) IgG antibody index. She was diagnosed with zoster sine herpete unilaterally affecting multiple lower cranial nerves. Although dysphagia is common in patients with PD, acute exacerbations of dysphagia require careful investigation of various potential causes, including VZV infection.

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Publication Details

Journal
Internal Medicine
Published
2024-09-03
DOI
https://doi.org/10.2169/internalmedicine.4250-24
Primary Topic
Herpesvirus Infections and Treatments
Type
article
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article

Zoster Sine Herpete Affecting Multiple Lower Cranial Nerves Presenting Severe Dysphagia in a Patient with Parkinson's Disease

Naoko Matsubara, Jun‐ichi Kira, Akira Yokote, Ayako Sakoda et al.
Internal Medicine
Herpesvirus Infections and Treatments
article

Zoster Sine Herpete Affecting Multiple Lower Cranial Nerves Presenting Severe Dysphagia in a Patient with Parkinson's Disease

Naoko Matsubara, Jun‐ichi Kira, Akira Yokote, Ayako Sakoda, Yasutaka Iwanaga, K. Yamashita, Keiko Haro, Y Kanamoto, Yuri Nakamura
article en

Abstract

We report the case of a 74-year-old woman with Parkinson's disease (PD) who developed acute dysphagia, dysarthria, and hoarseness. A neurological examination and nasopharyngeal fiberscopy revealed paralysis of the left glossopharyngeal, vagus, and hypoglossal nerves. No skin rash was observed. Cerebrospinal fluid testing showed lymphocytic pleocytosis, and an elevated varicella-zoster virus (VZV) IgG antibody index. She was diagnosed with zoster sine herpete unilaterally affecting multiple lower cranial nerves. Although dysphagia is common in patients with PD, acute exacerbations of dysphagia require careful investigation of various potential causes, including VZV infection.

Internal MedicineVol. 64(8)
Fukuoka International University (JP), Fukuoka Hospital (JP), International University of Health and Welfare (JP)
Openalex Percentile: Top 78%
Herpesvirus Infections and Treatments
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Zoster Sine Herpete Affecting Multiple Lower Cranial Nerves Presenting Severe Dysphagia in a Patient with Parkinson's Disease — Naoko Matsubara, Jun‐ichi Kira, et al. · Internal Medicine (2024) | TGRS Research Map | TGRS