Evaluation of antibacterial susceptibility profile in pregnant women with asymptomatic bacteriuria in Kadapa

: The bacterial urinary tract infection in pregnancy may be symptomatic (cystitis, pyelonephritis) or asymptomatic (bacteriuria without symptoms). Empirical antimicrobial therapy may be affected by resistance of uropathogens due to the irrational use of antibiotics. This prevalence of resistance is rising and varies across the globe due to different treatment recommendations which may be determined by taking into account frequently occurring infections, susceptibility patterns, evidence, physician acceptance, antimicrobial stewardship norms, availability of formularies, and antimicrobial prices. So the current research was carried out. : A cross-sectional study was conducted among pregnant women with UTI attending antenatal care (ANC) by excluding pregnant women who had taken antibiotics within the two weeks prior to their ANC follow-up and symptomatic UTI pregnant women. The antibiotic sensitivity of the uropathogens and their identification were evaluated by conventional culture, microbiological techniques and sensitivity tests. The results were analysed by SPSS software for descriptive statistics. : 377 pregnant women with UTI participated in the present study. The results demonstrated that most of the participants who lived in urban areas (64%) were affected. The results also suggest that 42% of participants who had secondary education as the highest level of education, 45% of participants belonged to an upper middle-class family and, 40% of working professionals in the study were affected. Out of 103 isolates, 79 isolates were gram negative & 24 were Gram positive. Out of seventy-nine gram negative isolates, the major contribution was by (36), . (26). Among 24 gram positive isolates, the major contribution was by Coagulase Negative Staphylococci (CONS) (12). The uropathogens were shown diverse antibiotic sensitivity for the study test drugs. : This study concludes that the antibacterial susceptibility and resistance of uropathogens may vary in different geographical areas based on antibiotic usage and circumstances. This study also demonstrated the imperative prerequisite of periodic assessments.