Correlation of adiponectin and leptin with BMI, blood pressure in patients with preeclampsia

The purpose of our research was to find out how serum levels of leptin and adiponectin are connected with preeclampsia and whether they may be used as biomarkers for the illness. Thirty (30) normal-pregnant patients and sixty (60) preeclamptic patients were included. Additionally, we included thirty (30) age- and BMI-matched healthy controls. Using an enzyme-linked immunosorbent assay, the amounts of leptin and adiponectin in the serum were measured. When compared to healthy controls and normal pregnant women, patients with mild and severe preeclampsia had significantly higher blood pressure, body mass index, serum adiponectin, and leptin levels. According to the individual's correlation analysis, blood pressure and body mass index were positively and statically linked with serum levels of adiponectin and leptin. The study's conclusions suggest that the markedly elevated serum levels of leptin and adiponectin could serve as an indicator of preeclampsia.