Association of Oncotype-DX HER2 Single Gene Score With HER2 Expression Assessed by Immunohistochemistry in HER2-low Breast Cancer

Oncotype-DX single-gene scores for HER2 are a potential surrogate marker for assessing the precise HER2 status, with better reproducibility and less interobserver variance compared to immunohistochemistry. The use of rt-PCR emerges as an alternative method of assessment of the HER2-low subgroup.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2024-09-01
DOI
https://doi.org/10.21873/cdp.10370
Citations
3
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.85
Controls
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article

Association of Oncotype-DX HER2 Single Gene Score With HER2 Expression Assessed by Immunohistochemistry in HER2-low Breast Cancer

Loukas Kontovinis, Ioannis Natsiopoulos, George Douganiotis, Konstantinos Papazisis et al.
3 citations
Cancer Diagnosis & Prognosis
HER2/EGFR in Cancer Research
0.85
article

Association of Oncotype-DX HER2 Single Gene Score With HER2 Expression Assessed by Immunohistochemistry in HER2-low Breast Cancer

Loukas Kontovinis, Ioannis Natsiopoulos, George Douganiotis, Konstantinos Papazisis, Thomas Zarampoukas
article en
3 citations

Abstract

Oncotype-DX single-gene scores for HER2 are a potential surrogate marker for assessing the precise HER2 status, with better reproducibility and less interobserver variance compared to immunohistochemistry. The use of rt-PCR emerges as an alternative method of assessment of the HER2-low subgroup.

Cancer Diagnosis & PrognosisVol. 4(5)
OncoMed (United States) (US), Interbalkan Medical Center (GR), Euromedica (GR), Hellenic Agency for Local Development and Local Government (GR)
Good health and well-being
Openalex Percentile: Top 23%
HER2/EGFR in Cancer Research
0.85
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