Cardiac biomarkers and effects of aficamten in obstructive hypertrophic cardiomyopathy: the SEQUOIA-HCM trial
N-Terminal pro-B-type natriuretic peptide and hs-cTnI concentrations are associated with key variables in obstructive hypertrophic cardiomyopathy. Serial measurement of NT-proBNP and hs-cTnI appears to reflect clinical response to aficamten therapy.
Authors
- Carolyn Yung Ho (ORCID: https://orcid.org/0000-0002-7334-7924)
- Roberto Barriales‐Villa (ORCID: https://orcid.org/0000-0002-6721-3487)
- Brian Lee Claggett (ORCID: https://orcid.org/0000-0002-4215-9218)
- Stephen B. Heitner (ORCID: https://orcid.org/0000-0003-2189-1474)
- Iacopo Olivotto (ORCID: https://orcid.org/0000-0003-1751-9266)
- Amy Wohltman
- Hugh Watkins (ORCID: https://orcid.org/0000-0002-5287-9016)
- ANJALI TIKU OWENS (ORCID: https://orcid.org/0000-0002-9669-8495)
- Caroline Coats (ORCID: https://orcid.org/0000-0002-3208-470X)
- James Louis Januzzi (ORCID: https://orcid.org/0000-0002-8338-1798)
- Scott David Solomon (ORCID: https://orcid.org/0000-0003-3698-9597)
- Albert Hagège (ORCID: https://orcid.org/0000-0003-4685-6077)
- Martin S. Maron (ORCID: https://orcid.org/0000-0002-9923-3853)
- Matthew M.Y. Lee (ORCID: https://orcid.org/0000-0001-9213-2067)
- Daniel Jacoby (ORCID: https://orcid.org/0000-0002-9182-275X)
- D. Marshall Brinkley (ORCID: https://orcid.org/0000-0002-9511-7767)
- Ahmad Masri (ORCID: https://orcid.org/0000-0002-6390-6526)
- Fady I. Malik (ORCID: https://orcid.org/0000-0002-5597-5759)
- Ian J. Kulac (ORCID: https://orcid.org/0000-0002-0710-1088)
- Stuart Kupfer (ORCID: https://orcid.org/0000-0002-5469-1287)
- Sheila M. Hegde (ORCID: https://orcid.org/0000-0001-8157-8899)
- Lisa Meng (ORCID: https://orcid.org/0000-0003-0229-1131)
- Theodore P. Abraham (ORCID: https://orcid.org/0000-0003-3411-1334)
- Jacob Tfelt‐Hansen (ORCID: https://orcid.org/0000-0003-3895-9316)
Institutions
- University of Copenhagen (DK)
- Brigham and Women's Hospital (US)
- Lahey Hospital and Medical Center (US)
- Harvard University (US)
- Oregon Health & Science University (US)
- University of California, San Francisco (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- University of Oxford (GB)
- Massachusetts General Hospital (US)
- Lahey Medical Center (US)
- Hôpital Européen (FR)
- Baim Institute for Clinical Research (US)
- Meyer Children's Hospital (IT)
- Cytokinetics (United States) (US)
- Complexo Hospitalario Universitario A Coruña (ES)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Instituto de Investigación Biomédica de A Coruña (ES)
- Vanderbilt Health (US)
- University of Glasgow (GB)
- University of Pennsylvania (US)
Publication Details
- Journal
- European Heart Journal
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1093/eurheartj/ehae590
- Citations
- 22
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 8.84
Funders
- Brigham and Women's Hospital
- Massachusetts General Hospital
- Yale University
- Vanderbilt University
- University of Pennsylvania
- Ohio State University
- Emory University
- NYU Langone Medical Center
- Northwestern University
- University of Chicago
- University of Minnesota
- Cleveland Clinic
- University of Utah
- University of Washington
- University of Texas Southwestern Medical Center
- University of South Carolina
- NHS Greater Glasgow and Clyde
- Royal Brompton and Harefield NHS Foundation Trust
- Cedars-Sinai Medical Center
- Vanderbilt University Medical Center
- University Hospitals Birmingham NHS Foundation Trust
- Cytokinetics
- Houston Methodist Hospital
- Queen Elizabeth Hospital Birmingham Charity
- Saint Luke's Health System
- University of Oxford
- Oxford University Hospitals NHS Foundation Trust
- St George's University Hospitals NHS Foundation Trust
- Barts Health NHS Trust
- University of California, San Francisco
- Houston Methodist Research Institute
- University of Chicago Medicine