[Study on direct ventricular assist loading mode based on a finite element method].

To investigate the biomechanical effects of direct ventricular assistance and explore the optimal loading mode, this study established a left ventricular model of heart failure patients based on the finite element method. It proposed a loading mode that maintains peak pressure compression, and compared it with the traditional sinusoidal loading mode from both hemodynamic and biomechanical perspectives. The results showed that both modes significantly improved hemodynamic parameters, with ejection fraction increased from a baseline of 29.33% to 37.32% and 37.77%, respectively, while peak pressure, stroke volume, and stroke work parameters also increased. Additionally, both modes showed improvements in stress concentration and excessive fiber strain. Moreover, considering the phase error of the assist device's working cycle, the proposed assist mode in this study was less affected. Therefore, this research may provide theoretical support for the design and optimization of direct ventricular assist devices.

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Publication Details

Journal
PubMed
Published
2024-08-25
DOI
https://doi.org/10.7507/1001-5515.202312070
Primary Topic
Cardiac Structural Anomalies and Repair
Type
article
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[Study on direct ventricular assist loading mode based on a finite element method].

Junbo Xu, Sheng Zhang, Gang Huang, Xiaohan Liu et al.
PubMed
Cardiac Structural Anomalies and Repair
article

[Study on direct ventricular assist loading mode based on a finite element method].

Junbo Xu, Sheng Zhang, Gang Huang, Xiaohan Liu, Yue Zhang, Chen Li, Zhongmin Jin, Xiaogang Zhang, Tianbo Wang, Xianjie Jiang
article en

Abstract

To investigate the biomechanical effects of direct ventricular assistance and explore the optimal loading mode, this study established a left ventricular model of heart failure patients based on the finite element method. It proposed a loading mode that maintains peak pressure compression, and compared it with the traditional sinusoidal loading mode from both hemodynamic and biomechanical perspectives. The results showed that both modes significantly improved hemodynamic parameters, with ejection fraction increased from a baseline of 29.33% to 37.32% and 37.77%, respectively, while peak pressure, stroke volume, and stroke work parameters also increased. Additionally, both modes showed improvements in stress concentration and excessive fiber strain. Moreover, considering the phase error of the assist device's working cycle, the proposed assist mode in this study was less affected. Therefore, this research may provide theoretical support for the design and optimization of direct ventricular assist devices.

PubMedVol. 41(4)
Southwest Jiaotong University (CN)
Cardiac Structural Anomalies and Repair
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