The utility of <scp>DNA</scp> methylation profiling in the diagnosis of un‐, de‐ and trans‐differentiated melanoma: a series of 11 cases
Despite loss of differentiation and phenotypical plasticity, methylation patterns seem to be retained in undifferentiated, de-differentiated and trans-differentiated melanomas and represent useful diagnostic tools to enhance diagnostic precision in these diagnostically challenging cases.
Authors
- Hester van Boven
- Daniel Baumhoer (ORCID: https://orcid.org/0000-0002-2137-7507)
- John S.A. Chrisinger (ORCID: https://orcid.org/0000-0002-7138-0923)
- Baptiste Ameline (ORCID: https://orcid.org/0000-0001-5913-7413)
- Zeynep Betül Erdem (ORCID: https://orcid.org/0000-0002-0840-4689)
- Judith V.M.G. Bovée (ORCID: https://orcid.org/0000-0003-1155-0481)
- Karen J. Fritchie (ORCID: https://orcid.org/0009-0009-3831-7496)
Institutions
- Cleveland Clinic (US)
- University of Basel (CH)
- Washington University in St. Louis (US)
- Leiden University Medical Center (NL)
- University Hospital of Basel (CH)
- The Netherlands Cancer Institute (NL)
Publication Details
- Journal
- Histopathology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1111/his.15309
- Citations
- 9
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.57