Cats with systemic ınflammatory response syndrome: granulocyte/lymphocyte ratio in hypothermia and hyperthermia conditions

Systemic inflammatory response syndrome (SIRS) is a conceptual framework developed to underscore the significance of systemic inflammation activation in precipitating organ dysfunction in cases of sepsis. This study endeavors to explore the interplay between hyperthermia, hypothermia, and the granulocyte-to-lymphocyte ratio (G/L) in feline patients diagnosed with SIRS. A total of 25 cats positive for SIRS were included in the study. The groups were determined as G1: ≤37.8 °C (n=8), G2: ≥39.7 °C (n=11) and G3: ≥40.0 °C (n=6). The G/L ratio has no statistical difference was found between G1 and G2, but G3 was found to have a statistically higher G/L ratio than G1 and G2. In conclusion, our findings suggest a potential association between temperature dysregulation and altered G/L ratios in feline SIRS cases. These results contribute to our understanding of the inflammatory response in cats and may inform future diagnostic and therapeutic strategies.