<scp>SOX</scp>‐5 Transcription Factor: a Novel Psoriatic Autoantigen Preferentially Found in Women
SOX-D transcription factors are novel psoriatic autoantigens. Anti-SOX5 antibodies were preferentially found in women with PsA and associated with specific clinical and treatment characteristics, suggesting that anti-SOX5 antibodies may identify mechanistic subgroups. We independently validated anti-ADAMTS-L5 autoantibodies in PsA.
Authors
- Livia Casciola‐Rosen (ORCID: https://orcid.org/0000-0002-4172-1539)
- Antony Rosen (ORCID: https://orcid.org/0000-0002-8374-4763)
- Qingyuan Yang (ORCID: https://orcid.org/0000-0001-8808-1113)
- Ana‐Maria Orbai (ORCID: https://orcid.org/0000-0001-8644-8567)
- David Fiorentino (ORCID: https://orcid.org/0000-0001-7951-3674)
- Erika Darrah (ORCID: https://orcid.org/0000-0003-1119-0279)
- Jamie Perin (ORCID: https://orcid.org/0000-0002-5482-6620)
- Laura Gutierrez‐Alamillo
- Michelle Petri (ORCID: https://orcid.org/0000-0003-1441-5373)
- Clifton O. Bingham (ORCID: https://orcid.org/0000-0002-4752-5029)
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/acr2.11740
- Citations
- 3
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Jerome L. Greene Foundation
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases