Phytochemical Screening and Antioxidant Activity of <i>Annona Senegalensis</i> Extracts (Leaves and Stem Bark) Collected from Three Regions of Senegal

The main objective of the present study is to focus on evaluation of the secondary metabolites composition and antioxidant activity of hydro – ethanolic extracts of <i>Annona senegalensis</i> leaves and stem bark which used in traditional medicine against several kind of diseases. The yields of hydro-ethanolic extracts of organs (leaves and Stem bark) were determined, followed by phytochemical screening and amount of secondary metabolites, by using conventional analytical methods. Anti-radical activity was carried out by DPPH (2, 2-diphenyl-l-picrylhydrazyl) reduction tests. The best extraction rates, whatever the plant organ or origin, were obtained with leaves (15.5% on average). Phytochemical screening revealed the presence of polyphenols, flavonoids and tannins. The highest levels of total polyphenols were obtained with leaves extracts [83.931 ± 0.018 g EGA/100 g Dry Matter (DM)] compared with stem bark (77.886 ± 1.001 g EGA/100 g DM). The highest tannin and flavonoid contents are 1.093 ± 0.006 g EC/100 g DM and 0.195 ± 0.004 g EC/100 g DM, respectively. Moreover, the extracts have a high antioxidant capacity with high inhibition percentages of 95.06 ± 0.10% for the leaves and 92.87 ± 0.10% for the bark. These results highlight the presence of bioactive compounds and potential antioxidant activity that have been shown to be efficient in the treatment of certain diseases, in accordance with ethno - botanical survey.