Highly sensitive blood-based biomarkers detection of beta-amyloid and phosphorylated-tau181 for Alzheimer’s disease
Plasma p-tau181 level and Aβ42/Aβ40 ratio showed promising values in diagnosis of AD and MCI. Our results indicate that this improved digital ELISA diagnosis approach can facilitate early recognition and management of AD and pre-AD patients.
Authors
- Yuanyuan Xu (ORCID: https://orcid.org/0000-0003-2354-9453)
- Lihui Yang
- Ying Meng (ORCID: https://orcid.org/0000-0003-3180-2404)
- Fangfang Zhu (ORCID: https://orcid.org/0000-0001-7358-2353)
- Guangli Shou
- Wanli Dong (ORCID: https://orcid.org/0000-0003-1000-3814)
- Fulin Guan
- Min Li (ORCID: https://orcid.org/0000-0002-5486-2947)
- Wei Yang (ORCID: https://orcid.org/0009-0005-8713-6262)
Institutions
- Soochow University (CN)
- The Second Affiliated Hospital of Bengbu Medical College (CN)
- First Affiliated Hospital of Soochow University (CN)
- The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.3389/fneur.2024.1445479
- Citations
- 6
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.96