Prenatal tobacco and alcohol exposure, white matter microstructure, and early language skills in toddlers from a South African birth cohort
Our findings show that prenatal alcohol and/or tobacco exposure appear to alter the relationship between white matter microstructure and early language skills in this population of toddlers, potentially laying the basis of language deficits observed later in older children with prenatal substance exposure, which may have implications for learning and interventions.
Authors
- Catherine J. Wedderburn (ORCID: https://orcid.org/0000-0002-4887-1644)
- Bryce Geeraert (ORCID: https://orcid.org/0000-0003-1388-1014)
- Nadia Hoffman (ORCID: https://orcid.org/0000-0002-7269-1416)
- Sivenesi Subramoney (ORCID: https://orcid.org/0000-0001-8947-439X)
- Annerine Roos (ORCID: https://orcid.org/0000-0001-6487-3159)
- Catherine A. Lebel (ORCID: https://orcid.org/0000-0002-0344-4032)
- Dan Joseph Stein (ORCID: https://orcid.org/0000-0001-7218-7810)
- Kirsten A. Donald (ORCID: https://orcid.org/0000-0002-0276-9660)
- Heather Joy Zar (ORCID: https://orcid.org/0000-0002-9046-759X)
- Katherine L. Narr (ORCID: https://orcid.org/0000-0002-9396-7936)
- Roger P. Woods (ORCID: https://orcid.org/0000-0001-9679-9571)
- Mohammad Ghasoub
- Shantanu H. Joshi (ORCID: https://orcid.org/0000-0003-1287-7005)
- C.M. Scholten
Institutions
- South African Medical Research Council (ZA)
- University of Cape Town (ZA)
- University of California, Los Angeles (US)
- University of Calgary (CA)
- Alberta Children's Hospital (CA)
- Brain Mapping Foundation (US)
- Red Cross War Memorial Children's Hospital (ZA)
- Hotchkiss Brain Institute (CA)
Publication Details
- Journal
- Frontiers in Integrative Neuroscience
- Published
- 2024-09-02
- DOI
- https://doi.org/10.3389/fnint.2024.1438888
- Citations
- 4
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.62