Causal pathways in preeclampsia: a Mendelian randomization study in European populations
This extensive MR study sheds light on the complex etiology of preeclampsia, underscoring the causal impact of specific metabolic, lipid, immune, lifestyle, and bone metabolism factors. Our findings advocate for a multidimensional approach to better understand and manage preeclampsia, paving the way for future research to develop targeted preventive and therapeutic strategies.
Authors
- Chao Pei
- Jianwu Shen (ORCID: https://orcid.org/0009-0005-6443-1111)
- Junru Li (ORCID: https://orcid.org/0000-0001-7603-8599)
- Yan Yang (ORCID: https://orcid.org/0000-0001-7167-0261)
- Yuxiao Huang
- Mengdi Ding
- Ran Luo
- Aochuan Sun (ORCID: https://orcid.org/0000-0002-3597-0504)
- Zilong Tan
- Sheng He (ORCID: https://orcid.org/0000-0002-5531-714X)
- Jing Hong
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Peking University Cancer Hospital (CN)
- Xiyuan Hospital (CN)
- China Academy of Traditional Chinese Medicine Hospital of Ophthalmology (CN)
- Qinghai Provincial Peoples Hospital (CN)
- Jiangsu Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.3389/fendo.2024.1453277
- Citations
- 5
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.91
Funders
- Zhejiang Chinese Medical University
- China Academy of Chinese Medical Sciences
- Servier