Targeting proliferating cell nuclear antigen enhances ionizing radiation‐induced cytotoxicity in prostate cancer cells
These data provide a strong rationale for the therapy studies using PCNA-I1S or R9-AR-PIP in combination with X-ray radiation against CRPC tumors in preclinical models.
Authors
- Michael Lamba (ORCID: https://orcid.org/0000-0001-6714-8702)
- Jiang Wang (ORCID: https://orcid.org/0009-0008-9688-4416)
- Shan Lu (ORCID: https://orcid.org/0000-0001-9864-1831)
- Zhongyun Dong (ORCID: https://orcid.org/0000-0003-3906-301X)
Institutions
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- The Prostate
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/pros.24786
- Citations
- 3
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- U.S. Department of Defense
- DOD Prostate Cancer Research Program