Comparative study on structural and functional brain differences in mild cognitive impairment patients with tinnitus
The MCI-T group exhibited greater β-amyloid accumulation in the auditory cortex and more extensive changes across various brain networks compared with the MCI-NT group, potentially leading to diverse clinical symptoms such as dementia with semantic deficits or depression. Tinnitus in MCI patients may serve as a biomarker for degenerative changes in the temporal lobe and alterations in brain network dynamics.
Authors
- Yu Kyeong Kim (ORCID: https://orcid.org/0000-0002-3282-822X)
- Yejin Yun (ORCID: https://orcid.org/0000-0002-0719-9599)
- Sun‐Won Park (ORCID: https://orcid.org/0000-0002-5063-2685)
- Sang‐Yoon Han (ORCID: https://orcid.org/0000-0002-4014-8531)
- Young Ho Kim (ORCID: https://orcid.org/0000-0001-8889-3285)
- Min Jae Lee (ORCID: https://orcid.org/0000-0002-3252-6467)
- Heejung Kim (ORCID: https://orcid.org/0000-0001-6215-5639)
- JunYoung Lee
Institutions
- Seoul National University (KR)
- Seoul Metropolitan Government (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Hanyang University (KR)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2024-09-02
- DOI
- https://doi.org/10.3389/fnagi.2024.1470919
- Citations
- 4
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- National Research Foundation
- Seoul National University
- National Research Foundation of Korea
- College of Medicine, Seoul National University