Causal associations between gut microbiota and premature rupture of membranes: a two-sample Mendelian randomization study
In this study, we have discovered a causal relationship between the presence of specific probiotics and pathogens in the host and the risk of PROM. The identification of specific gut microbiota associated with PROM through MR studies offers a novel approach to diagnosing and treating this condition, thereby providing a new strategy for clinically preventing PROM.
Authors
- Yan Su (ORCID: https://orcid.org/0000-0002-1546-2799)
- Xinyuan Zhang (ORCID: https://orcid.org/0000-0002-4636-1202)
- Jiafeng Huang (ORCID: https://orcid.org/0009-0001-7598-7431)
- Qin Zou (ORCID: https://orcid.org/0000-0001-7955-0782)
- Qian Li (ORCID: https://orcid.org/0000-0003-1697-235X)
- Chunli Li (ORCID: https://orcid.org/0000-0002-9071-161X)
- Hua Zou (ORCID: https://orcid.org/0000-0002-5822-5507)
- Lei Zhang (ORCID: https://orcid.org/0009-0005-3737-0739)
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.3389/fimmu.2024.1440232
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Chongqing Postdoctoral Science Foundation
- Centre Scientifique et Technique du Bâtiment