Exploring the Bioactive Constituents and Pharmacological Activity of Scutellaria baicalensis Georgi, or Chinese Skullcap

Introduction: Scutellaria baicalensis Georgi, a plant with therapeutic properties, has been extensively utilized in China for centuries. The extract derived from its roots is commonly referred to as Huang-Qin. Materials and Methods: The informative data were gathered from many electronic databases, including Scopus, Science Direct, PubMed, and Web of Science. The study criteria for selection included analyzing scientific manuscripts that specifically investigated phytoconstituents and their pharmacological effects. The keywords used were Scutellaria baicalensis, bioactive components, and pharmacological profile. Discussion: The main concern of this study is to enhance the accessibility of extensive research discoveries about the pharmacological potential of S. baicalensis. Results: S. baicalensis root has been utilized to manage dysentery, diarrhea, hypertension, insomnia, inflammation, respiratory infections, and hemorrhaging. Wogonoside and baicalin are the primary bioactive constituents obtained from S. baicalensis root. The flavones have been documented to possess many pharmacological properties, such as hepatoprotective, anti-cancer, antibacterial, antioxidant, antiviral, neuroprotective, and anticonvulsant activities. Conclusion: This manuscript's main concern is to enhance the accessibility of extensive research discoveries about the pharmacological potential of S. baicalensis.