The Effect of Hydroxysafflor Yellow A on Inflammatory Injury in LPS-induced Endothelial Cell Injury Model through TLR4/NF-κB Pathway Based on Network Pharmacology and Experimental Verification

HSYA may reduce inflammation and oxidative stress by inhibiting the expression of the TLR4 / NF-κB-related signaling pathway, therefore protecting endothelial cells, which might be a potential mechanism of HSYA in ISSNHL treatment.

Authors

Feida Fu
Qinghua Guo (ORCID: https://orcid.org/0000-0002-5180-7854)
Wandong She (ORCID: https://orcid.org/0000-0003-1923-8687)
Xiaoyan Zhu (ORCID: https://orcid.org/0000-0002-1574-8762)
Xiaoyang Zhang (ORCID: https://orcid.org/0009-0006-7836-1465)
Xu Wang (ORCID: https://orcid.org/0000-0002-2092-4054)

Institutions

Nanjing University of Chinese Medicine (CN)
Nanjing Traditional Chinese Medicine Hospital (CN)
Nanjing Drum Tower Hospital (CN)
Suzhou Municipal Hospital (CN)

Publication Details

Journal: Current Pharmaceutical Biotechnology
Published: 2024-09-02
DOI: https://doi.org/10.2174/0113892010311334240816101114
Citations: 1
Primary Topic: Sunflower and Safflower Cultivation
Type: article
Field-Weighted Citation Impact: 0.60

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article

The Effect of Hydroxysafflor Yellow A on Inflammatory Injury in LPS-induced Endothelial Cell Injury Model through TLR4/NF-κB Pathway Based on Network Pharmacology and Experimental Verification

Feida Fu, Qinghua Guo, Wandong She, Xiaoyan Zhu et al.

Sep 2, 2024

1 citations

Current Pharmaceutical Biotechnology

Sunflower and Safflower Cultivation

0.60

article

The Effect of Hydroxysafflor Yellow A on Inflammatory Injury in LPS-induced Endothelial Cell Injury Model through TLR4/NF-κB Pathway Based on Network Pharmacology and Experimental Verification

Feida Fu, Qinghua Guo, Wandong She, Xiaoyan Zhu, Xiaoyang Zhang, Xu Wang

September 2, 2024article en

1 citations

Abstract

HSYA may reduce inflammation and oxidative stress by inhibiting the expression of the TLR4 / NF-κB-related signaling pathway, therefore protecting endothelial cells, which might be a potential mechanism of HSYA in ISSNHL treatment.

Current Pharmaceutical BiotechnologyVol. 26(6)

Nanjing University of Chinese Medicine (CN), Nanjing Traditional Chinese Medicine Hospital (CN), Nanjing Drum Tower Hospital (CN), Suzhou Municipal Hospital (CN)

Good health and well-being

Openalex Percentile: Top 22%

Sunflower and Safflower Cultivation

0.60

DOI Source OpenAlex

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The Effect of Hydroxysafflor Yellow A on Inflammatory Injury in LPS-induced Endothelial Cell Injury Model through TLR4/NF-κB Pathway Based on Network Pharmacology and Experimental Verification — Feida Fu, Qinghua Guo, et al. · Current Pharmaceutical Biotechnology (2024) | TGRS Research Map | TGRS