Prognostic significance of low HER2 expression in gastric cancer: a retrospective, single-center analysis
This study highlights the prognostic importance of low HER2 expression in gastric cancer, similar to that observed in HER2-low-positive breast cancer, and suggests reclassification of gastric cancer to improve personalized treatment. Future studies should elucidate the molecular underpinnings of low HER2 expression in gastric cancer to guide novel therapeutic strategies and improve outcomes.
Authors
- Yusuke Gokon (ORCID: https://orcid.org/0000-0002-6163-4117)
- Yuka Nakashima
- Toshiaki Kashiwadate (ORCID: https://orcid.org/0000-0002-5049-2467)
- Keiichiro Hatoyama (ORCID: https://orcid.org/0000-0003-2421-9659)
- Kenji Shimizu (ORCID: https://orcid.org/0000-0002-4865-2222)
- Takayuki Abe (ORCID: https://orcid.org/0000-0003-4184-0527)
- Takahiro Ogino
- Koichiro Sato
- Kazunori Katsura
- Yusuke Ohki
Institutions
- Iwate Prefectural Central Hospital (JP)
- Miwa Hospital (JP)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1186/s12885-024-12749-x
- Citations
- 3
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.85