The safety of a dolutegravir (DTG)-based antiretroviral treatment (ART) regimen for pregnancy and birth outcomes in Ethiopia: evidence from multicenter cohort study
In this study, we observed that DTG-based regimens were associated with better pregnancy and birth outcome safety profiles, reaffirming the WHO recommendation. However, a prospective study is recommended to assess uncaptured maternal and perinatal adverse outcomes, such as congenital abnormalities, and infant growth and neurocognitive development.
Authors
- Birkneh Tilahun Tadesse (ORCID: https://orcid.org/0000-0003-4005-8605)
- Eyasu Makonnen (ORCID: https://orcid.org/0000-0002-9259-5288)
- Eleni Aklillu (ORCID: https://orcid.org/0000-0002-9788-0790)
- Abel Gedefaw (ORCID: https://orcid.org/0000-0002-5541-0088)
- Yifru Berhan (ORCID: https://orcid.org/0000-0002-3779-0718)
- Stefano Vella (ORCID: https://orcid.org/0000-0003-2347-5984)
Institutions
- Karolinska University Hospital (SE)
- Hawassa University (ET)
- Karolinska Institutet (SE)
- Africa Centres for Disease Control and Prevention (ET)
- St. Paul's Hospital Millennium Medical College (ET)
- Addis Ababa University (ET)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1186/s12879-024-09763-6
- Citations
- 3
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- London School of Hygiene and Tropical Medicine
- European and Developing Countries Clinical Trials Partnership