Fine-Scale Haplotype Mapping Reveals an Association of the FTO Gene with Osteoporosis and Fracture Risk in Postmenopausal Women
Concordant associations with OP, an increased fracture risk, and a lower BMD at all skeletal sites indicate that the <i>FTO</i> gene is a promising candidate for OP, explaining the complex relationship with obesity and offering new perspectives for the study of the epigenetic regulation of bone metabolism.
Authors
- Corinne Lautier (ORCID: https://orcid.org/0000-0002-3229-191X)
- Dana Manda (ORCID: https://orcid.org/0000-0001-9190-837X)
- Daniela Greere (ORCID: https://orcid.org/0000-0001-7198-6573)
- Sara Haydar (ORCID: https://orcid.org/0000-0003-0795-1733)
- Florin Grigorescu (ORCID: https://orcid.org/0000-0002-3095-5639)
- Gabriela Voicu
- Cătălina Poiană
Institutions
- University of Copenhagen (DK)
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement (FR)
- Carol Davila University of Medicine and Pharmacy (RO)
- Institut National des Langues et Civilisations Orientales (FR)
- Université de Montpellier (FR)
- Novo Nordisk Foundation (DK)
- Institutul Național de Endocrinologie C.I. Parhon (RO)
- Institut Agro Montpelier (FR)
- Institut de Recherche pour le Développement (FR)
Publication Details
- Journal
- Genes
- Published
- 2024-09-01
- DOI
- https://doi.org/10.3390/genes15091152
- Citations
- 3
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Universitatea de Medicină şi Farmacie "Carol Davila" Bucureşti