Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum

This research employs Aegle marmelos gum in various ratios as a natural polymer to formulate and assess Propranolol hydrochloride floating tablets. Because of its high solubility and permeability, propranolol hydrochloride, a non-selective beta-adrenergic receptor blocker, has a restricted bioavailability. Floating tablets are intended to improve the absorption and bioavailability of drugs by staying afloat in the stomach. Aegle marmelos gum (AMG) was used as a polymer in varied ratios to create distinct formulations. The tablets were then tested for a number of characteristics, including hardness, friability, drug content, in vitro buoyancy, and drug release profiles. The findings showed that the Aegle marmelos gum content had a major impact on the tablets' floating qualities and drug release characteristics.

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Publication Details

Journal
Journal of Advances in Science and Technology
Published
2024-09-02
DOI
https://doi.org/10.29070/f97k6921
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
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article

Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum

Eman Nazmi Al Qutub Dr. Eman Nazmi Al Qutub, Khoulod Nazmi Al Qutub Dr. Khoulod Nazmi Al Qutub, Dr. Dr. Manal Nazmi Al Qutub Dr. Dr. Manal Nazmi Al Qutub
Journal of Advances in Science and Technology
Natural Antidiabetic Agents Studies
article

Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum

Eman Nazmi Al Qutub Dr. Eman Nazmi Al Qutub, Khoulod Nazmi Al Qutub Dr. Khoulod Nazmi Al Qutub, Dr. Dr. Manal Nazmi Al Qutub Dr. Dr. Manal Nazmi Al Qutub
article en

Abstract

This research employs Aegle marmelos gum in various ratios as a natural polymer to formulate and assess Propranolol hydrochloride floating tablets. Because of its high solubility and permeability, propranolol hydrochloride, a non-selective beta-adrenergic receptor blocker, has a restricted bioavailability. Floating tablets are intended to improve the absorption and bioavailability of drugs by staying afloat in the stomach. Aegle marmelos gum (AMG) was used as a polymer in varied ratios to create distinct formulations. The tablets were then tested for a number of characteristics, including hardness, friability, drug content, in vitro buoyancy, and drug release profiles. The findings showed that the Aegle marmelos gum content had a major impact on the tablets' floating qualities and drug release characteristics.

Journal of Advances in Science and TechnologyVol. 20(2)
Princess Nourah bint Abdulrahman University (SA), American Pharmacists Association (US)
Clean water and sanitation
Openalex Percentile: Top 77%
Natural Antidiabetic Agents Studies
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Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum — Eman Nazmi Al Qutub Dr. Eman Nazmi Al Qutub, Khoulod Nazmi Al Qutub Dr. Khoulod Nazmi Al Qutub, et al. · Journal of Advances in Science and Technology (2024) | TGRS Research Map | TGRS