Studies on Propranolol hydrochloride floating tablets formulated with different concentrations of Aegle marmelos gum
This research employs Aegle marmelos gum in various ratios as a natural polymer to formulate and assess Propranolol hydrochloride floating tablets. Because of its high solubility and permeability, propranolol hydrochloride, a non-selective beta-adrenergic receptor blocker, has a restricted bioavailability. Floating tablets are intended to improve the absorption and bioavailability of drugs by staying afloat in the stomach. Aegle marmelos gum (AMG) was used as a polymer in varied ratios to create distinct formulations. The tablets were then tested for a number of characteristics, including hardness, friability, drug content, in vitro buoyancy, and drug release profiles. The findings showed that the Aegle marmelos gum content had a major impact on the tablets' floating qualities and drug release characteristics.
Authors
- Eman Nazmi Al Qutub Dr. Eman Nazmi Al Qutub
- Khoulod Nazmi Al Qutub Dr. Khoulod Nazmi Al Qutub
- Dr. Dr. Manal Nazmi Al Qutub Dr. Dr. Manal Nazmi Al Qutub
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- American Pharmacists Association (US)
Publication Details
- Journal
- Journal of Advances in Science and Technology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.29070/f97k6921
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00