Scrub Typhus Meningoencephalitis Presenting as Generalized Convulsive Status Epilepticus with Basal Ganglia and Extra-limbic Cortical Involvement, Complicated by Cortical Multifocal Myoclonus

Scrub typhus can be a significant diagnostic challenge, potentially presenting with generalized convulsive status epilepticus and mimicking both clinical and radiological features of arboviral encephalitides, such as those caused by West Nile and Japanese encephalitis viruses. Furthermore, as demonstrated in this case, its radiological presentation can resemble that of autoimmune encephalitis. Given that scrub typhus is amenable to treatment with antibiotics, such as doxycycline and azithromycin, which do not increase seizure risk, it should be considered in the differential diagnosis for patients presenting with seizures or encephalitis, especially in endemic areas.

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Publication Details

Journal
The Neurohospitalist
Published
2024-09-02
DOI
https://doi.org/10.1177/19418744241276903
Citations
6
Primary Topic
Infectious Encephalopathies and Encephalitis
Type
article
Field-Weighted Citation Impact
2.33

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article

Scrub Typhus Meningoencephalitis Presenting as Generalized Convulsive Status Epilepticus with Basal Ganglia and Extra-limbic Cortical Involvement, Complicated by Cortical Multifocal Myoclonus

Moisés León‐Ruiz, Julián Benito‐León, Uttam Biswas, Ritwik Ghosh et al.
6 citations
The Neurohospitalist
Infectious Encephalopathies and Encephalitis
2.33
article

Scrub Typhus Meningoencephalitis Presenting as Generalized Convulsive Status Epilepticus with Basal Ganglia and Extra-limbic Cortical Involvement, Complicated by Cortical Multifocal Myoclonus

Moisés León‐Ruiz, Julián Benito‐León, Uttam Biswas, Ritwik Ghosh, Raghul Bheeman, Ritun Sarkar, Arpan Mukhopadhyay
article en
6 citations

Abstract

Scrub typhus can be a significant diagnostic challenge, potentially presenting with generalized convulsive status epilepticus and mimicking both clinical and radiological features of arboviral encephalitides, such as those caused by West Nile and Japanese encephalitis viruses. Furthermore, as demonstrated in this case, its radiological presentation can resemble that of autoimmune encephalitis. Given that scrub typhus is amenable to treatment with antibiotics, such as doxycycline and azithromycin, which do not increase seizure risk, it should be considered in the differential diagnosis for patients presenting with seizures or encephalitis, especially in endemic areas.

The NeurohospitalistVol. 15(2)
Universidad Complutense de Madrid (ES), Burdwan Medical College & Hospital (IN), Hospital Universitario La Paz (ES), Research Institute Hospital 12 de Octubre (ES), Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
European Commission, Ministerio de Economía y Competitividad, Ministerio de Ciencia e Innovación, National Institutes of Health, National Institute of Neurological Disorders and Stroke
Good health and well-being
Openalex Percentile: Top 11%
Infectious Encephalopathies and Encephalitis
2.33
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Scrub Typhus Meningoencephalitis Presenting as Generalized Convulsive Status Epilepticus with Basal Ganglia and Extra-limbic Cortical Involvement, Complicated by Cortical Multifocal Myoclonus — Moisés León‐Ruiz, Julián Benito‐León, et al. · The Neurohospitalist (2024) | TGRS Research Map | TGRS