Understanding Macrophage Interaction with Antimony-Doped Tin Oxide Plasmonic Nanoparticles
Antimony-doped tin oxide nanoparticles (ATO NPs) have emerged as a promising tool in biomedical applications, namely robust photothermal effects upon near-infrared (NIR) light exposure, enabling controlled thermal dynamics to induce spatial cell death. This study investigated the interplay between ATO NPs and macrophages, understanding cellular uptake and cytokine release. ATO NPs demonstrated biocompatibility with no impact on macrophage viability and cytokine secretion. These findings highlight the potential of ATO NPs for inducing targeted cell death in cancer treatments, leveraging their feasibility, unique NIR properties, and safe interactions with immune cells. ATO NPs offer a transformative platform with significant potential for future biomedical applications by combining photothermal capabilities and biocompatibility.
Authors
- Sandeep Keshavan (ORCID: https://orcid.org/0000-0002-2403-4083)
- Alke Petri‐Fink (ORCID: https://orcid.org/0000-0003-3952-7849)
- О.A. Balitskii (ORCID: https://orcid.org/0000-0001-9395-4871)
- Viktoriya Ivasiv (ORCID: https://orcid.org/0000-0002-8093-0499)
- Aura Maria Moreno‐Echeverri (ORCID: https://orcid.org/0000-0002-6855-1402)
- José Muñetón Díaz (ORCID: https://orcid.org/0009-0004-4698-1067)
- Phattadon Yajan (ORCID: https://orcid.org/0000-0003-4325-2016)
- Barbara Rothen‐Rutishauser (ORCID: https://orcid.org/0000-0002-7805-9366)
- Maria Porteiro-Figueiras
- Mira Witzig
Institutions
- University of Waterloo (CA)
- University of Fribourg (CH)
- Adolphe Merkle Institute (CH)
- University of Minho (PT)
Publication Details
- Journal
- Cells
- Published
- 2024-09-01
- DOI
- https://doi.org/10.3390/cells13171468
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.18
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Fundação para a Ciência e a Tecnologia