Prevalence and Risk Factors for Malignant Nodal Involvement in Early Esophago-Gastric Adenocarcinoma

This large multicenter data set suggests that early EG adenocarcinoma is associated with significant risk of LNM. These data are representative of current real clinical practice with ER-based staging, and suggests previously held beliefs regarding reliability of predictive factors for LNM may need to be reconsidered. Further research to identify patients who may benefit from organ-preserving versus surgical treatment is urgently required.

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Publication Details

Journal
Annals of Surgery
Published
2024-09-02
DOI
https://doi.org/10.1097/sla.0000000000006496
Citations
5
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
2.09
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article

Prevalence and Risk Factors for Malignant Nodal Involvement in Early Esophago-Gastric Adenocarcinoma

Tim Underwood, Swathikan Chidambaram, Ewen A. Griffiths, James Gossage et al.
5 citations
Annals of Surgery
Gastric Cancer Management and Outcomes
2.09
article

Prevalence and Risk Factors for Malignant Nodal Involvement in Early Esophago-Gastric Adenocarcinoma

Tim Underwood, Swathikan Chidambaram, Ewen A. Griffiths, James Gossage, Nigel John Trudgill, Natalie Blencowe, Tom Crosby, Philip H. Pucher, Pradeep Bhandari, Sivesh Kathir Kamarajah, Sheraz Markar, Saqib Rahman, Richard Evans
article en
5 citations

Abstract

This large multicenter data set suggests that early EG adenocarcinoma is associated with significant risk of LNM. These data are representative of current real clinical practice with ER-based staging, and suggests previously held beliefs regarding reliability of predictive factors for LNM may need to be reconsidered. Further research to identify patients who may benefit from organ-preserving versus surgical treatment is urgently required.

Annals of SurgeryVol. 281(3)
University Hospitals Birmingham NHS Foundation Trust (GB), St Thomas' Hospital (GB), Guy's and St Thomas' NHS Foundation Trust (GB), Velindre NHS Trust (GB), Oxford Health NHS Foundation Trust (GB), University Hospital Southampton NHS Foundation Trust (GB), University of Bristol (GB), University of Oxford (GB), Portsmouth Hospitals NHS Trust (GB), Queen Elizabeth Hospital (GB), Pulp and Paper Research Institute (SK), Institute for Conflict Research (GB), Imperial College London (GB), University of Birmingham (GB)
Good health and well-being
Openalex Percentile: Top 12%
Gastric Cancer Management and Outcomes
2.09
DOIOpen Access PDFOpenAlex
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