Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study
This exploratory study shows that prebiotic consumption by lactating mothers selectively alters specific immunomodulatory proteins in HM. This finding is crucial for understanding how prebiotic dietary recommendations for pregnant and lactating women can modify the immune properties of HM and potentially influence infant health outcomes through immune support from breastfeeding.
Authors
- Johan Garssen (ORCID: https://orcid.org/0000-0002-8678-9182)
- Debra J. Palmer (ORCID: https://orcid.org/0000-0003-2498-8343)
- Matthew N. Cooper (ORCID: https://orcid.org/0000-0003-1139-3682)
- Valérie Verhasselt (ORCID: https://orcid.org/0000-0002-5732-9048)
- Desiree Silva (ORCID: https://orcid.org/0000-0003-4454-466X)
- Jeffrey A. Keelan (ORCID: https://orcid.org/0000-0002-5403-6266)
- Chitra Saraswati
- Patrícia Macchiaverni (ORCID: https://orcid.org/0000-0002-1897-9013)
- Susan L. Prescott (ORCID: https://orcid.org/0000-0003-4845-8590)
- C. Christophersen (ORCID: https://orcid.org/0000-0003-1591-5871)
- Nivedithaa Divakara
- Zac Dempsey (ORCID: https://orcid.org/0009-0006-5698-7803)
Institutions
- Edith Cowan University (AU)
- The Kids Research Institute Australia (AU)
- The University of Western Australia (AU)
- Utrecht University (NL)
- Curtin University (AU)
- Princess Margaret Hospital for Children (AU)
- Government of Western Australia Department of Health (AU)
- Queen Elizabeth II Medical Centre (AU)
- Nutricia Research (Netherlands) (NL)
- Perth Children's Hospital
Publication Details
- Journal
- Pediatric Allergy and Immunology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/pai.14226
- Citations
- 6
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.86
Funders
- Family Larsson‐Rosenquist Foundation
- Australian Government
- Paul Ramsay Foundation
- Medical Research Council
- National Health and Medical Research Council