Clinical outcomes of first-line combination therapy with immune checkpoint inhibitor for metastatic non-clear cell renal cell carcinoma: a multi-institutional retrospective study in Japan
This study confirms clinical benefit of ICI combination therapy for metastatic nccRCC patients in real-world settings. Furthermore, the effectiveness of combination therapy was comparable between patients aged < 75 and those ≥75 years with respect to clinical prognosis.
Authors
- Masao Tsujihata
- Gaku Yamamichi
- Koji Hatano (ORCID: https://orcid.org/0000-0002-8409-5152)
- Atsunari Kawashima (ORCID: https://orcid.org/0000-0001-9369-4264)
- Kyosuke Matsuzaki (ORCID: https://orcid.org/0000-0002-7137-1162)
- Yu Ishizuya (ORCID: https://orcid.org/0000-0003-0778-1308)
- Hitoshi Inoue (ORCID: https://orcid.org/0000-0001-5859-4217)
- Shingo Toyoda (ORCID: https://orcid.org/0009-0008-2572-5071)
- Mototaka Sato (ORCID: https://orcid.org/0000-0001-5270-3021)
- Tetsuya Takao (ORCID: https://orcid.org/0000-0003-1223-8158)
- Wataru Nakata (ORCID: https://orcid.org/0000-0003-3953-6534)
- Syunsuke Inoguchi
- Kazutoshi Fujita (ORCID: https://orcid.org/0000-0002-6774-7497)
- Taigo Kato (ORCID: https://orcid.org/0000-0002-8681-1407)
- Kazuo Nishimura (ORCID: https://orcid.org/0000-0002-7644-1350)
- Masashi Nakayama (ORCID: https://orcid.org/0009-0009-2093-9107)
- Kensaku Nishimura
- Norio Nonomura (ORCID: https://orcid.org/0000-0002-6522-6233)
- Osamu Miyake
- Yoshiyuki Yamamoto (ORCID: https://orcid.org/0000-0003-4830-5703)
- Shingo Takada
- Akihiro Yoshimura
- Yasutomo Nakai
- Yohei Okuda (ORCID: https://orcid.org/0000-0001-9909-4200)
Institutions
- Osaka Prefectural Medical Center (JP)
- Toyonaka Municipal Hospital (JP)
- Osaka National Hospital (JP)
- Kindai University Hospital (JP)
- Osaka City General Hospital (JP)
- Ikeda Municipal Hospital (JP)
- Osaka Police Hospital (JP)
- Osaka Rosai Hospital (JP)
- Osaka International Cancer Institute (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- International Journal of Clinical Oncology
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1007/s10147-024-02612-1
- Citations
- 6
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Osaka University