RIPK1 inhibition mitigates neuroinflammation and rescues depressive-like behaviors in a mouse model of LPS-induced depression
These findings propose RIPK1 as a pivotal mediator in regulating neuroinflammation and neural plasticity, highlighting its significance as a potential therapeutic target for depression.
Authors
- Tahir Ali (ORCID: https://orcid.org/0000-0002-2138-1303)
- Shupeng Li (ORCID: https://orcid.org/0000-0002-7807-374X)
- Axiang Li
- Xiaoming Yu (ORCID: https://orcid.org/0000-0003-1564-4549)
- Liang Hao (ORCID: https://orcid.org/0000-0001-7207-9131)
- Ruyan Gao
- Canyu Yang
- Qichao Gong
- Tao Li (ORCID: https://orcid.org/0000-0003-1368-0212)
- Hu Yue (ORCID: https://orcid.org/0009-0008-3399-0983)
- Shengnan Mou
- Yanhua Luo (ORCID: https://orcid.org/0000-0002-5929-6083)
- Liufang He
Institutions
- University of Toronto (CA)
- Peking University (CN)
- Second Hospital of Shandong University (CN)
- ShenZhen People’s Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
- Southern Medical University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1186/s12964-024-01796-3
- Citations
- 22
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.46
Funders
- National Natural Science Foundation of China
- Shenzhen-Hong Kong Institute of Brain Science