Fetal microchimerism cells suppress arthritis progression by inducing CD14+ IL‐10+ cells in pregnant experimental mice
Our investigations demonstrated that the FMCs protected the CIA mice from cartilage damage and triggered an immunosuppressive response in them by increasing the number of CD14<sup>+</sup> IL10<sup>+</sup> cells. In conclusion, the FMCs could potentially exhibit protective properties within the context of inflammatory arthritis that arises during pregnancy.
Authors
- Da‐Wei Chang (ORCID: https://orcid.org/0000-0002-7410-2339)
- Deh‐Ming Chang (ORCID: https://orcid.org/0000-0003-0888-5205)
- F. C. Liu
- Chen‐Chih Chu (ORCID: https://orcid.org/0000-0002-1599-0305)
- C.-C. Wu
- Chun–Chi Lu
Institutions
- Tri-Service General Hospital (TW)
- Taipei Veterans General Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/1756-185x.15322
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Taipei Veterans General Hospital